Searchable abstracts of presentations at key conferences in endocrinology

ea0092op-11-05 | Oral Session 11: Autoimmunity / Hyperthyroidism | ETA2023

Association between thyroid function and osteoarthritis: a population-based cohort study

Xu Yanning , Szilagyi Ingrid , Boer Cindy , Sedaghati-Khayat Bahar , Edward Visser W. , van Meurs Joyce , Chaker Layal

Background: Previous genetic and animal studies implied a potential association between thyroid hormone and osteoarthritis (OA), but this has not been confirmed in the general population. We aim to investigate whether thyroid function is associated with hand, hip or knee OA.Methods: We included 9,054 participants from Rotterdam Study with baseline measurement of thyroid-stimulating hormone (TSH), free thyroxine (FT4) and radiographs. Joint radiographs we...

ea0084op-06-28 | Oral Session 6: Hypothyroidism | ETA2022

The optimal ranges of thyroid function based on the risk of cardiovascular disease and mortality: an individual participant data meta-analysis

Xu Yanning , Derakhshan Arash , Wildisen Lea , Hysaj Ola , Iacoviello Massimo , Ceresini Graziano , Ferrucci Luigi , Iervasi Giorgio , Pingitore Alessandro , Vaes Bert , Gussekloo Jacobijn , Medici Marco , Galesloot Tessel , P. F. Dullaart Robin , J.L. Bakker Stephan , Wouter Jukema J. , Trompet Stella , Westendorp Rudi , Ittermann Till , Volzke Henry , Dorr Marcus , Schmidt Borge , Fuhrer Dagmar , J. Wareham Nicholas , Boelaert Kristien , Razvi Salman , P. J. Vanderpump Mark , Muendlein Axel , Drexel Heinz , Bensenor Isabela , Sgarbi Jose , C. Bauer Douglas , A. Fink Howard , M. Rhee Connie , Azizi Fereidoun , Imaizumi Misa , B. Yeap Bu , Hankey Graeme , J. Brown Suzanne , P. Walsh John , Korevaar Tim , Rodondi Nicolas , R. Cappola Anne , Peeters Robin , Chaker Layal , the Thyroid Studies Collaboration for

Background and Objective: Thyroid function reference ranges are statistically defined by the 2.5th and 97.5th percentiles, which do not account for potential risk of clinical outcomes. We aimed to define the optimal ranges of thyroid-stimulating hormone (TSH) and free thyroxine (FT4), based on the risk of cardiovascular disease (CVD) and mortality.Methods: We performed an individual-participant data analysis and identified prospecti...